The Comparison of Epirubicin and Mitomycin by Bladder Instillation for The Superficial Bladder Cancer
Objective To compare the effect on recurrence and safety of Epirubicin and Mitomycin(MMC) by bladder instillation after transurethral resection of superficial bladder carcinoma. Methods 106 patients of superficial bladder carcinoma were randomly divided into two groups respectively. During the chemotherapy, blood liver and kidney function tests were tested Regularly. Follow-up cystoscopy for recurrence of tumor was record. Results 9(17.6%) cases of recurrence was observed in Epirubicin group in the first year after operation, with an mean follow up time of 17.1-month. 10(18.2%%) cases of recurrence was observed in MMC group in the first year after operation, with an mean follow up time of 16.4-month. The incidence of localized side effects was 58.8%(30/51) in Epirubicin group. And in MMC group, the incidence of side effects was 56.4%(31/55). No statistics difference between lolized side effects was observed. Conclusion There were no statistical difference for the effect of recurrence and safety between Epirubicin and MMC by bladder instillation after transurethral resection of superficial bladder carcinoma.
NETL
NSTL
万方数据
维普
