Relative risk factors for cerebral microbleeds in acute cerebral infraction patients
Objective To investigate the incidence of cerebral microbleeds(CMB) in patients with acute cerebral infarction and analyze its risk factors. Methods 122 patients with acute cerebral infarction admitted to our hospital from March 2008 to March 2012 were divided into CMB group(n=51) and non-CMB group(n=71) according to their MRI susceptibility-weighted imaging. General clinical data and biochemical variables were compared between two groups to explore relative risk factors of CMB. The patients were divided into three groups according to the extent of the CMB, and the relationship between carotid IMT level and the degree of CMB were analysised. Results The LDL levels were significantly lower while the HDL level was significantly higher in CMB group than non-CMB group(P<0.05). The proportion of age, hypertension, stroke history and history of smoking in the CMB groups were significantly higher than the non-CMB group(P<0.05). The abnormal rate of IMT in CMB group were significantly higher than the non-CMB group(χ2=7.05, P<0.05), and The abnormal rate of IMT among mild, moderate and severe CMB groups also have a significant difference(χ2=8.83, P=0.02). Conclusion Age, hypertension, stroke history, smoking history, intimal thickening in the carotid artery, serum HDL and LDL levels are all risk factors for CMBs.