Patients with chronic hepatitis b virus and serological sign and pathological correlation studies
Objective In patients with chronic hepatitis b virus and serological sign and pathological correlation study. Methods Select 29 patients with hepatitis b, confirmed have positive serological marker repeated abnormal liver function, liver puncture by the immunohistochemical and pathologic examination of serum hepatitis virology monitoring blood coagulation function and liver function tests,adopting fluorescence quantitative polymerase chain reaction(PCR) in serum of patients with hepatitis b virus DNA(HBV DNA) levels were detected. Result Through to the staging of liver fibrosis and inflammation grading comparison between groups of serum HBV DNA level of quantitative detection. The differences were not statistically significant(P>0.05); HBV DNA negative and positive in all patients with pathological indicators did not appear obvious difference, not statistically significant(P>0.05); For hepatitis b patients and hepatitis b patients between related data index found after comparison, the difference is not statistically significant(P>0.05). Conclusion As the change of clinical symptoms, the serological marker of patients with chronic viral hepatitis liver fibrosis pathological change. Adoption of serological indexes and liver biopsy comprehensive detection method has higher diagnosis value.
NETL
NSTL
万方数据
维普
