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乳腺原发性平滑肌肉瘤临床病理观察

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目的探讨乳腺原发性平滑肌肉瘤的临床病理特征。方法报告1例乳腺原发性平滑肌肉瘤,结合文献分析其临床表现、病理特征和免疫组化表达。结果乳腺原发性平滑肌肉瘤表现为单个肿块,无其它临床症状,辅助检查无特征性阳性,术前难以确诊。组织学上由密集的梭形细胞构成,呈束状、编织状排列。瘤细胞有明显异型性及更多的核分裂。免疫组化显示瘤细胞表达Vimentin、Desmin和SMA。结论乳腺原发性平滑肌肉瘤是一种少见的高度恶性肿瘤,确诊依靠病理检查,手术完整切除是目前主要的治疗方法。
Objective To study the clinical and pathological features of primary leiomyosarcoma of the breast. Methods One case of primary leiomyosarcoma of the breast were reported with clinical data, pathological features, phenotype of IHC,and review of literature. Results The primary leiomyosarcoma of the breast showed single mass, and didn't have any features of symptoms and auxiliary examination, and it was difficult to make correct diagnosis before operation. Histologic examination showed that the tumor was composed of relatively uniform spindly cells arranged in interlacing fascicles. The tumor cells proliferated with obvious atypia, and it had many mitotic rate. With IHC staining, the cells were positive forVimentin, Desmin and SMA. Conclusions Primary leiomyosarcoma of the breast is rare,but can be diagnosed properly based on pathological features. Surgical resection is the effective method.

BreastPrimary leiomyosarcomaClinicopathology

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江西省赣州市赣县人民医院病理科

乳腺 平滑肌肉瘤 临床病理

2013

中国医疗前沿
中国医院协会

中国医疗前沿

影响因子:0.186
ISSN:1673-5552
年,卷(期):2013.(8)
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