Diagnostic Value of Neutrophil CD64 Using ROC Curve in bacterial meningitis
Objective To evaluate the value Neutrophil CD64 in the diagnosis of bacterial meningitis by Receiver Operating Characteristic curves(ROC). Methods 40 patients with bacterial meningitis(confirmed by cerebrospinal fluid) were obtained for CD64 and CD11b, measurement, blood routin test. 20 non-infected, healthy children cases were seted as control group. Their blood samples were obtained for CD64 and CD11b. Results Draw the ROC curve of the levels of CD64, CD11b in diagnosing bacterial meningitis. The area under the ROC curve were 0.880, 0.853; The best cutoff value of CD64, CD11b were 1.30, 15.85; the sensitivity were 88.3%, 70.4%; the specificity were 90.4%, 75.9%; The coefficients between CD64 and WBC, CD11b and WBC were 0.284, 0.293(P>0.05), no liner correlation. Conclusion ROC analysis showed that Neutrophil CD64 for the bacterial meningitis diagnosis has higher diagnostic accuracy, CD64 is an ideal diagnostic marker to early identify bacterial meningitis.
NETL
NSTL
万方数据
维普
