Flow cytometric analysis of peripheral blood T lymphocyte subpopulation in persons infected with primary syphilis
Objective Flow cytometric were applied to detect T lymphocyte subpopulations in patients infected with primary syphilis, to know the change of cell-mediated immunity and to offer theory base to clinical treatment. Methods Flow cytometric were applied to detect CD3+, CD4+ and CD8+ lymphocyte in peripheral blood from 19 volunteers, including 7 patients infected with primary syphilis and 12 normal human. Results Although CD3+, CD4+, CD8+ and CD4+/CD8+ were higher in primary syphilis , but there were not significant(P>0.05). With ulcer appearing, CD4+/CD8+ were lower in the first week but higher in the second than normal average value. Conclusions With ulcer appearing, Cytoimmunity in primary syphilis can be depress or enhance. Cytoimmunity depresses in first week and enhances in second week.
NETL
NSTL
万方数据
维普
