The clinical investgatton of different doses of atorvastatin in unstable angina pectoris
Objective To abserve the influenct of different doaes of atorvastatin an the prognosis of unstable angina. Methods 78 cases of patients treated with unstable angina were randomly divided into two groups. In the control groups, 39 patients accepted conventional treatments and Atorvastatin 20mg/d, while in the treatment groups 39 patients accepted conventional treatment and Atorvastatin 40mg/d. Both groups were measured before and after 180d treatment at the four lipids, CRP, and were observed of Re-angina, myocardial infarction and cardiac death and other undesirable occurrence of cardiovascular events. Results The lipid levels of two youps have varying degrees of reduction after treatment. Compared with the control group, the observation group is more obvious(P<0.05). The two groups both reduce CRP level after treatment. Compared with the control group, the effect of the abservation group is more obvious(P<0.05). With the occurrence of adverse events, the observation group decreased signiificantly compared with the control group(P<0.05). Conclusion Atorvastatin intensive treatment can improve the prognosis of patients with unstable angina and intensive treatment after weigh in patients with drug use pros and cons, recommended 40mg/d.
AtorvastatinUnstable anginaLipidC-reactive protein