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黄连解毒汤联合二甲双胍治疗2型糖尿病的临床观察

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目的观察黄连解毒汤联合二甲双胍对2型糖尿病患者血糖血脂及空腹胰岛素、胰岛素抵抗、胰岛素敏感指数的影响。方法选取2012年3月-2012年9月于我院就诊的54例2型糖尿病患者为研究对象,随机将其分为中药组、西药组、联合组,统计分析三组患者治疗后的观察指标。结果联合组空腹血糖、胰岛素抵抗、糖化血红蛋白、甘油三酯、胆固醇、低密度脂蛋白均明显低于其他两组,胰岛素敏感指数、空腹胰岛素较其他两组明显升高,差异有统计学意义(P<0.01)。结论黄连解毒汤联合二甲双胍有良好的控制血糖、调节血脂的功效,可以降低胰岛素抵抗,提高胰岛素敏感指数。
Clinical observation of Huanglian Jiedu decoction combined with Metformin in treating Type 2 Diabetes mellitus
Objective To observe the effects of Huanglian Jiedu decoction combined with metformin on blood glucose, blood lipid,fasting insulin, insulin resistance, insulin sensitivity index in patients with type 2 diabetes. Method Selection 54 patients with type 2 diabetes from 2012.3 to 2012.9 in our hospital as the research object, randomly divided into traditional Chinese medicine group, western medicine group, combined group, then index of the three groups of patients after the statistics and analysis. Results The fasting blood glucose, insulin resistance, glycosylated hemoglobin, triglyceride, cholesterol, low density lipoprotein of combined groupwere significantly lower than the other two groups, insulin sensitive index, fasting insulin than the other two groups increased significantly, the results are significantly different(P<0.01). Conclusion Huanglian Jiedu decoction combined with metformin has good control of blood glucose, regulating blood lipid effect, reduce insulin resistance, improve insulin sensitivity index.

Huanglian Jiedu DecoctionMetforminType 2 diabetesClinical observation

杨文军、赵兴国

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250014 济南山东中医药大学附属医院内分泌科

250011 山东中医药大学第一临床学院2010级

黄连解毒汤 二甲双胍 2型糖尿病 临床观察

2009-088

2013

中国医疗前沿
中国医院协会

中国医疗前沿

影响因子:0.186
ISSN:1673-5552
年,卷(期):2013.(9)
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