The detection and Significance to plasma brain natriuretic peptide and d-dimer for the coronary heart disease
Objective To Investigate the clinical significance of the plasma brain natriuretic peptide and d-dimer for the diagnosis to the coronary heart disease. Method To choose 109 definite CHD cases by coronary angiography, who had no liver/kidney damage、tumor and other diseases. They were to be three clinical classification: acute myocardial infarction(AMI), unstable angina pectoris(UAP), stable angina pectoris(SAP). The control group were 109 cases health examinations. Those were to detect plasma brain natriuretic peptide and d-dimer concentration. Result The plasma brain natriuretic peptide and d-dimer concentration of the CHD group were significantly higher than those of the control group(P<0.05), the level of brain natriuretic peptide and d-dimer in AMI group is obviously higher than those in UAP group, the level of brain natriuretic peptide and d-dimer in UAP group is obviously higher than those of the SAP group, the difference between groups were statistically significant(P<0.05). Conclusion The level of plasma brain natriuretic peptide and d-dimer are significantly increased in CHD, which are regarded as the CHD index for the diagnosis, treatment and prognosis.
NETL
NSTL
万方数据
维普
