Bedside rapid determination of type B urine sodium peptide on the value of early diagnosis and treatment of heart & nbsp;failure analysis
Objective To investigate the bedside rapid determination of type B urine sodium Peptide(Brain Natriuretic Peptide, BNP) on heart failure in the early diagnosis and curative effect evaluation of application value. Methods For 2008 to 2012 in our hospital, 384 cases of suspected heart failure patients with ecg, X-ray chest radiograph, and cardiac ultrasound measurement, according to the measurement results are divided into heart failure(HF) group 89 cases and the heart failure group(not a HF group) 295 cases, conventional western medicine therapy in patients with HF group, respectively, before the medication, medication for 24 h, 48 h, 72 h to determination of venous blood plasma BNP level, and compared with the HF group differences; To 295 patients with HF group according to the cardiac function(NYHA grading) is divided into Ⅱ level of 121 cases Ⅲ level of 101 cases and Ⅳ 73 cases, respectively, in the treatment of venous blood was taken before and after the determination of plasma BNP levels and compare groups of patients. Results HF group and HF group comparison: before medication, HF plasma BNP levels were significantly higher than in patients with HF group(P<0.05); After medication, plasma BNP levels in patients with HF group continues to decline, and medication, medication before 24h, 48h, 72h, all have significant difference(P<0.05); Use basic dropped to normal level after 72h, and the HF group no significant difference(P>0.05). HF group internal grading comparison: before the treatment, Ⅱ, Ⅲ, Ⅳ plasma BNP levels in patients with elevated, and between different groups had significant difference(P<0.05); After treatment, patients with all levels of plasma BNP levels were significantly decreased(P<0.05), after the fall of water still showed a trend of increase Ⅱ, Ⅲ, Ⅳ, and significant difference between group and group(P<0.05). Conclusion Bedside rapid determination of BNP on heart failure of early diagnosis, illness evaluation and treatment efficacy of real-time monitoring has a certain value, the application in the diagnosis and treatment of heart failure in clinical work with deeper mining potential.
The BNP rapid determinationHeart failureDiagnosisTreatmentApplication value
NETL
NSTL
万方数据
维普
