Analysis of curative effect of Yigan Decoction Combined with bicyclol tablets in the treatment of chronic hepatitis B
Objective Discussion on Yigan Decoction Combined with bicyclol tablets in treatment of liver stagnation and spleen deficiency syndrome of chronic hepatitis b curative effect and safety. Methods Selection of patients with chronic hepatitis B, 81 cases of liver stagnation and spleen deficiency type, were randomly divided into traditional Chinese medicine combined with bicyclol group (combined group) 41 cases, 40 cases of bicyclol group. Chinese medicine group were treated with Decoction of Chinese medicine, Each time 200ml, daily, the afternoon of the 1 times; bicyclol group received daily oral bicyclol tablets 75mg, treatment for 24 weeks, stop drug 12 weeks of observation. Changes of serum ALT, AST were compared and GGT. Results After twenty-fourth weeks treatment, the recovery rate of ALT(85.3%): combined with bicyclol group(75%), no significant difference. AST, the recovery rate of GGT: the combined group(65.8%, 75.6%) of bicyclol group(37.5%, 35%), P <0.05. Twelfth weeks after stopping drug, ALT, AST, GGT sustained recovery rate: the combined group(66.6%, 50%, 56.7%) Bicyclol group(51.7%, 25%, 21.4%), P <0.05. No adverse events related to drug. Conclusion Bicyclol tablets combined with traditional Chinese medicine Yigan Decoction in the treatment of liver stagnation and spleen deficiency syndrome of chronic hepatitis B, compared with the sole use of bicyclol tablets have better protecting liver, reducing enzyme action, and security.
Chronic hepatitis BBicyclol tabletsYigan DecoctionStagnation of liver-QI with deficiency of the spleen
NETL
NSTL
万方数据
维普
