摘要
目的探讨影响妊娠合并慢性再生障碍性贫血并发子痫前期的相关危险因素,为妊娠合并慢性再生障碍性贫血并发子痫前期的预防提供帮助。方法选择并分析我院2007年5月-2012年12月住院合妊娠合并慢性再生障碍性贫血27例的临床资料,统计分析其年龄、首诊孕期、出血倾向、再障的严重程度、白细胞<4×109/L、血红蛋白<60g/L、血小板<10×109/L、血脂异常等因素对患者并发子痫前期的影响程度。结果血红蛋白<60g/L、血小板<10×109/L影响妊娠合并慢性再生障碍性贫血并发子痫前期的易感因素(P <0.05),而年龄、首诊孕期、有无出血倾向、再障的严重程度、白细胞<4×109/L等因素无统计学意义(P >0.05)。结论妊娠合并慢性再生障碍性贫血并发子痫前期受到多种因素影响,血红蛋白<60g/L、血小板<10×109/L是主要的相关危险因素。
Abstract
Objective To investigate the risk factor of pregnancy with chronic aplastic anemia and pre-eclampsia factors, for provide the help for prevention of pregnancy complicated with chronic aplastic anemia and pre-eclampsia. Methods 27 cases of pregnancy complicated with chronic aplastic anemia clinical data in our hospital from 2007 May and analysis to 2012 December, and the statistical analysis, the age, first diagnosed during pregnancy, bleeding tendency, aplastic anemia severity, white blood cell, hemoglobin, platelet <4×109/L<60g/L<10×109/L, such as abnormal blood lipid factors in patients with pre-eclampsia complicated influence factors. Results The factor of hemoglobin <60g/L, platelet <10×109/L affects pregnancy associated with chronic aplastic anemia and elicitors preeclampsia(P <0.05), and the age of first diagnosis, pregnancy, there is no bleeding tendency, aplastic anemia severity, leukocyte <4× 109/L factors and pregnancy complicated with chronic aplastic anemia and pre-eclampsia relationship no statistical significance(P >0.05). Conclusion Pregnancy complicated with chronic aplastic anemia and pre-eclampsia may affected by many factors, but the <60g/L hemoglobin, platelet <10×109/L is the major related Risk factors.