养胃颗粒的镇痛抗炎作用研究
Experimental study of The Analgesia and Anti-inflammatory Effects of Yangwei Granules
吴康郁 1朱群娣 2刘香英 1钟碧莲1
作者信息
- 1. 510240 广州中医药大学附属骨伤科医院
- 2. 510120 广东省中医院
- 折叠
摘要
目的探讨养胃颗粒的镇痛抗炎作用。方法取养胃颗粒配制的不同剂量对实验小鼠给药，应用醋酸致小鼠扭体法、小鼠热板法、二甲苯致小鼠耳廓肿胀法研究其镇痛抗炎作用。结果养胃颗粒可减少醋酸致小鼠扭体次数，延长小鼠舔足时间，减轻二甲苯致小鼠耳廓肿胀程度。结论养胃颗粒具有一定的镇痛抗炎效果。
Abstract
Objective To investigate the analgesia and anti-inflammatory effects of Yangwei Granules. Methods The anti-inflammatory and analgesia effects were observed by means of acetic acid inducing mouse writhing model, hot plate method and dimethylbenzene inducing ear edema model. Results It was found that Yangwei Granules significantly reducing the writhing frequency inducing by acetic acid, markedly increasing the pain threshold in mice induced by hot plate, evidently suppressing the mouse’s ear edema induced by dimethylbenzene. Conclusions The Yangwei Granules has anti-inflammatory and analgesic effects.
关键词
养胃颗粒/镇痛/抗炎Key words
Yangwei Granules/Analgesic/Anti-inflammatory引用本文复制引用
出版年
2013
NETL
NSTL
维普
万方数据