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脂蛋白α检测对糖尿病足的诊断价值分析

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目的探讨脂蛋白α检测对糖尿病足诊断的价值。方法以我院2009年1月-2012年12月间27例糖尿病足病患者为研究对象,将27例未患有糖尿病足病的糖尿病患者作为对照,比较两组患者在糖尿病相关生化指标和糖尿病足病相关脂蛋白指标间的差异。结果两组患者在TG、TC、HEL-C、LDL-C、FPG、ApoA、ApoB、ApoE含量方面无显著差异,观察组脂蛋白α浓度高于对照组,差异有统计学意义(P <0.05)。在Logistic多因素回归分析中,对糖尿病患者是否发生糖尿病足病有较为显著的影响是患者的性别、糖尿病病程及脂蛋白α的含量。结论脂蛋白α可以作为糖尿病足病诊断的重要指标。
The Effect Analysis of Lipoprotein α in the Diagnosis of Diabetic Foot
Objective To analysis the effect of lipoprotein α in the diagnosis of diabetic foot. Methods 27 cases with diabetic foot were in the study as the objective group, and 27 cases without diabetic foot were in the study as the control group. The difference of the diabetes related biochemical indicators and diabetic foot disease related indicators were compared. Result There was no significant difference between the two groups except the lipoprotein α. In the logistic regression analysis, the sex, the time diabetes duration and the level of lipoprotein α had a significant relationship with the diabetic foot. Conclusion It would get a satisfactory effect to use lipoprotein α as a predictor in the diagnosis of Diabetic foot.

Lipoprotein αDiabetic footDiagnosis

郭铁成、钟晓红、鄢燕琼、肖水平、高文

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518067 广东省深圳市蛇口人民医院内分泌科

脂蛋白α 糖尿病足病 诊断

2013

中国医疗前沿
中国医院协会

中国医疗前沿

影响因子:0.186
ISSN:1673-5552
年,卷(期):2013.(11)
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