The related factors of postoperative intracranial infections in neurosurgery and the distribution and antibiotic resistance of bacteria in patients with postoperative intracranial infections
Objective To investigate the factors of postoperative intracranial infections in neurosurgery and the distribution and antibiotic resistance of bacteria in patients with postoperative intracranial infections, and to provide valuable information for prophylactic and empirical antibiotic use in postoperative intracranial infection. Methods Totally 1600 patients who had a neurosurgical operation from Jan 2006 to Dec 2011 were chosen. Most related factors that may cause infection were studied retrospectively. At equal pace to studied common infection bacterial and bacterial antibiotic resistance. Results Totally 151 cases of 1600 patients were diagnosed as postoperative intracranial infection, infection rate is 9.44%. To confirm common infection pathogenic bacterium and sensitive drug through cultivation of scalp specimens and cerebrospinal fluid, drug sensitivity test. Conclusions Postoperative intracranial infections of neurosurgery involve in many factors. The most factor is communication of Intracranial and extracranial. The prevailing pathogenic bacterium in postoperative intracranial infection are Gram-positive cocci. Broad-spectrum antibiotic for Gram-positive cocci is prefer.