Analysis on 21 Cases of Adverse Drug Reaction by Clindamycin Injection
Objective To explore the rules and causes of adverse reactions by using Clindamycin Injection. Methods Analysing 21 patients' basic, primary disease, the incidence of adverse reactions who causing adverse drug reactions by Clindamycin Injection. Result 21 cases of Clindamycin injection adverse reactions in patients with women slightly more than men, but there is no statistical significant(P >0.05); 60 years old or more accounted for 17 cases of adverse reactions in patients, under the age of 60 accounted for 4 cases, with statistically significant(P <0.05); 21 patients' primary disease are infectious diseases; adverse reactions occur in 15min-45min accounted for 16 cases, compared to <15min and >45min group, the difference was statistical significant(P <0.05); clinical manifestations of adverse reactions included the skin and appendages (9 cases), systemic reactions(6 cases), cardiovascular system damage(3 cases), respiratory system damage(3 cases). Conclusion Clindamycin injection adverse reactions caused no significant relationship with patients' gender, adverse reactions mostly occurred in patients over the age of 60, the adverse reaction time more appear in 30min after administration, adverse reactions more performance for the damage to the skin and its appendages, in severe cases, there will be anaphylactic shock, chest tightness, shortness of breath and other symptoms with patients.
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NSTL
万方数据
维普
