焦虑抑郁情绪障碍对2型糖尿病患者胰岛素敏感性的影响
The effect of insulin sensitivity of anxiety depression mood disorders in type 2 diabetes patients
李杨梅 1张超1
作者信息
- 1. 611830 四川省都江堰市人民医院内科
- 折叠
摘要
目的观察焦虑抑郁情绪对2型糖尿病(T2DM)患者的胰岛素敏感性。方法对本院2010年5月-2011年7月98例糖尿病患者行汉密尔顿焦虑抑郁量表评分，并其分为焦虑抑郁合并T2DM组(试验组)和T2DM组(对照组)，分别检测其空腹血糖、空腹胰岛素，计算胰岛素抵抗指数(HOMA-IR)、胰岛素敏感指数(HOMA-IS)和胰岛分泌指数(HOMA-β)。结果试验组HOMA-IR、HOMA-β高于对照组，HOMA-IS低于对照组，差异均有统计学意义(P <0.01)。结论焦虑抑郁情绪障碍可导致T2DM患者的胰岛素敏感性下降。
Abstract
Objective To observe the emotional anxiety depression in patients with type 2 diabetes insulin sensitivity. Methods Our analysis in May 2010-July 2011 98 cases of patients with diabetes, and on the anxiety Hamilton depression rating scale, which is divided into two groups: the anxiety depression combination and type 2 diabetes group(experimental group) and type 2 diabetes group(control group) were detected the fasting blood glucose and fasting insulin, the calculation of insulin resistance index(HOMA-IR), insulin sensitivity index(HOMA-IS) and islet secretion index(HOMA-beta). Results The experimental group of HOMA-IR, HOMA-β, than the control group, the difference was statistically significant; experimental group of HOMA-IS below control group, the difference was statistically significant(P <0.01). Conclusion Anxiety depression mood disorders can result in patients with type 2 diabetes insulin sensitivity decline.
关键词
焦虑抑郁情绪障碍/2型糖尿病/HOMA-IR-/HOMA-IS-HOMA-βKey words
Anxiety depression mood disorders/T2DM/HOMA-IR/HOMA-IS/HOMA-β引用本文复制引用
出版年
2013
NETL
NSTL
维普
万方数据