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焦虑抑郁情绪障碍对2型糖尿病患者胰岛素敏感性的影响

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目的观察焦虑抑郁情绪对2型糖尿病(T2DM)患者的胰岛素敏感性。方法对本院2010年5月-2011年7月98例糖尿病患者行汉密尔顿焦虑抑郁量表评分,并其分为焦虑抑郁合并T2DM组(试验组)和T2DM组(对照组),分别检测其空腹血糖、空腹胰岛素,计算胰岛素抵抗指数(HOMA-IR)、胰岛素敏感指数(HOMA-IS)和胰岛分泌指数(HOMA-β)。结果试验组HOMA-IR、HOMA-β高于对照组,HOMA-IS低于对照组,差异均有统计学意义(P <0.01)。结论焦虑抑郁情绪障碍可导致T2DM患者的胰岛素敏感性下降。
The effect of insulin sensitivity of anxiety depression mood disorders in type 2 diabetes patients
Objective To observe the emotional anxiety depression in patients with type 2 diabetes insulin sensitivity. Methods Our analysis in May 2010-July 2011 98 cases of patients with diabetes, and on the anxiety Hamilton depression rating scale, which is divided into two groups: the anxiety depression combination and type 2 diabetes group(experimental group) and type 2 diabetes group(control group) were detected the fasting blood glucose and fasting insulin, the calculation of insulin resistance index(HOMA-IR), insulin sensitivity index(HOMA-IS) and islet secretion index(HOMA-beta). Results The experimental group of HOMA-IR, HOMA-β, than the control group, the difference was statistically significant; experimental group of HOMA-IS below control group, the difference was statistically significant(P <0.01). Conclusion Anxiety depression mood disorders can result in patients with type 2 diabetes insulin sensitivity decline.

Anxiety depression mood disordersT2DMHOMA-IRHOMA-ISHOMA-β

李杨梅、张超

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611830 四川省都江堰市人民医院内科

焦虑抑郁情绪障碍 2型糖尿病 HOMA-IR- HOMA-IS-HOMA-β

2013

中国医疗前沿
中国医院协会

中国医疗前沿

影响因子:0.186
ISSN:1673-5552
年,卷(期):2013.(12)
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