Right dexmedetomidine compared with midazolam mechanical ventilation sedative efficacy analysis
Objective To investigate the dexmedetomidine given sedation in acute exacerbation of chronic obstructive pulmonary disease(COPD) clinical efficacy in respiratory failure. Method From June 2011 to June 2012 in our hospital with chronic obstructive pulmonary disease and respiratory failure, 30 cases of invasive mechanical ventilation in patients treated using a random number table, were randomly divided into 2 groups, given sedative dexmedetomidine group. Result Test group average blood pressure, heart rate, oxygen saturation and the control group, no significant difference(P >0.05); ventilator time, delirium, ventilator-associated pneumonia incidence is lower than the midazolam group(P <0.05). Conclusions Chronic obstructive pulmonary disease and respiratory failure, the use of dexmedetomidine given a sedative can be accelerated in patients with offline, improved patient outcomes.