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房颤患者幽门螺杆菌感染与血脂关系探讨

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目的探讨房颤患者幽门螺杆菌(Hp)的感染与脂质代谢水平变化的相关性。方法选择55例房颤患者为研究对象,另外选择55例健康体检人员为对照。分别采用酶联免疫吸附测定法(ELISA)以及免疫比浊法检测Hp特异性抗体IgG(Hp IgG)浓度,并检测血清脂质,分析Hp感染与脂类物质浓度之间的关系。结果房颤组与对照组HpIgG阳性率比较,差异无统计学意义;血清总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)的浓度均明显高于对照组,高密度脂蛋白胆固醇(HDL-C)浓度明显低于对照组,差异均有统计学意义;Hp感染阳性房颤患者的血清TC、TG、LDL-C浓度均明显高于Hp感染阴性患者,而HDL-C浓度明显低于Hp感染阴性患者,差异均有统计学意义。结论 Hp感染与房颤本身没有明显相关性,但Hp感染可能通过对脂质代谢水平的影响而促进房颤的发展和演进。
Relationship between helicobacter pylori infection and blood-lipoids of atrial fibrillation patients
Objective To study Hp infection in patients with atrial fibrillation and lipid metabolism changes of correlation. Methods 55 patients with atrial fibrillation as the research object, in addition choose 55 cases of Hp examination personnel for reference. Respectively using ELISA and immune turbidimetric method to detect HpIgG expression level, and detect the serum lipid, analysis of Hp infection and the relationship between lipid concentrations. Results HpIgG positive rate compared with the control group, there was no statistically significant difference;Serum TC, TG, LDL-C concentrations were significantly higher than that of control group, HDL-C concentrations significantly lower than the control group, the difference had statistical significance; Positive Hp infection in patients with atrial fibrillation in the concentration of serum TC, TG, LDL -C were significantly higher than negative of Hp infection in patients, and Hp infection in HDL-C concentration significantly lower than the negative patients, the difference had statistical significance. Conclusion Hp infection have no obvious correlation with the incidence of atrial fibrillation itself, but the Hp infection may be through the influence on blood lipid metabolism and promote the development of atrial fibrillation and evolution.

Atrial fibrillationHpBlood-lipoids

潘敏、徐晖

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434020 湖北省荆州市第五人民医院检验科

房颤 幽门螺杆菌 血脂

2013

中国医疗前沿
中国医院协会

中国医疗前沿

影响因子:0.186
ISSN:1673-5552
年,卷(期):2013.(12)
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