摘要
目的比较子宫颈癌术后盆腔复发不同射野数目调强放疗(IMRT)计划的靶区和危及器官剂量学差异。方法10例子宫颈癌术后盆腔复发的病例，分别设计5、7及9野的IMRT计划，比较各计划间靶区剂量学特点及危及器官的受照射剂量及体积。结果5F-IMRT、7F-IMRT及9F-IMRT计划的靶区V95%、D95%及剂量的适形性与均匀性未见统计学差异。危及器官的受照射剂量及体积，各IMRT计划之间的差异无统计学意义。结论子宫颈癌术后盆腔复发放疗，在靶区的剂量分布和正常器官保护方面，5、7及9野的IMRT计划相比未见优劣。
Abstract
Objective To compare the dosimetric difference in planning target volumn and organ at risk(OAR) between intensity modulated radiation therapy(IMRT) plans with different beam arrangements. Methods Ten patients with recurrent cervical cancer were included in the study. For each patient, three IMRT treatment plans with 5,7and 9 beam fields were designed respectively. The target volume dose , conformal index(CI), homogeneity index(HI), and the dose and volume radiated of the OAR were compared. Results There was no significant differences among the IMRT plans in target volume dose, CI, HI. The dose and volumes of OAR among the IMRT plans were no significantly different. Conclusion In the dose distribution of target and the protection of normal structures, there was no obvious advantage among the 5-field IMRT, 7-field IMRT and 9-field IMRT plans in treating recurrent cervical cancer.
NETL
NSTL
维普
万方数据