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糖尿病患者消化间期胃肠运动规律的研究

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目的观察2型糖尿病患者消化间期胃肠运动的特征。方法选取我院2011年10月-2013年1月收治的57例2型糖尿病患者设为实验组,选取同期25名健康志愿者设为对照组。用胃十二指肠测压技术对两组人员进行消化间期胃肠移行性复合运动(MMC)检测,测定时间240-360min。结果实验组患者MMC正常者明显低于对照组(P<0.01),实验组MMCⅢ期缺失者高于对照组(P<0.01),MMCⅡ期持续时间长于对照组(P<0.05),MMCⅢ期胃窦部收缩频率和波幅低于对照组(P<0.05)。结论糖尿病患者消化间期胃肠运动障碍可主要表现为MMC Ⅲ期缺失、Ⅱ期持续时间延长以及胃窦部收缩力减弱,胃十二指肠测压可作为糖尿病患者胃肠运动功能障碍诊断及治疗的有效措施。
Observation on the regular pattern of interdigestive gastrointestinal motility in type 2 diabetes mellitus
Objective To observe the characteristics of interdigestive gastrointestinal motility in type 2 diabetes mellitus. Methods 57 type 2 diabetes patients were selected from our hospital from October 2011 to January 2013 as the Experimental group and 25 healthy volunteers as the Control group. Then interdigestive gastrointestinal motility of 2 groups were detected by interdigestive gastrointestinal manometry, and the time lasted for 240-360minutes. Results The cases of integral MMC in type 2 diabetes patients, which was decreased than that of Control group(P<0.01); PhaseⅢ were absent of Experimental group and Control group(P<0.01); The amplitude of MMCⅢ in antrum was lower in the Experimental group than that in the Control group(P<0.05). Conclusion Absence of MMCⅢ, Period of MMCⅡis prolonged and Reduction of Shrinkage force in antrum are the main characteristics of interdigestive gastrointestinal motility disorders in type 2 diabetes mellitus, the gastroduodenal manometry can be an effective method in the treatment and early diagnosis of patients with diabetes.

Type 2 diabetes mellitusInterdigestive gastrointestinal manometryMigrating motor complex

饶时春

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331300 江西省吉安市新干县人民医院内二科

2型糖尿病 胃十二指肠测压 消化间期移行性复合运动

2013

中国医疗前沿
中国医院协会

中国医疗前沿

影响因子:0.186
ISSN:1673-5552
年,卷(期):2013.(14)
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