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腹腔镜胃旁路手术治疗2型糖尿病单中心经验

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目的探讨腹腔镜胃旁路手术治疗2型糖尿病的临床效果及治疗体会。方法分析我院2010年8月-2012年2月开展腹腔镜胃旁路手术治疗糖尿病的20例病例资料,观察患者手术前后空腹血糖、体重指数、胰岛素抵抗(HOMA-IR)、糖化血红蛋白(HbAlc)、c肽等指标的改变。结果20例患者术后1个月血糖均有明显下降,葡萄糖耐量明显增强(P<0.05),12例患者术后1个月体重指数变化明显,15例术后随访3-12月,血糖在正常范围,不需胰岛素或药物控制;4患者例术后6个月, HOMA-IR、HbAlc与手术前相比明显降低(P<0.05);糖尿病相关并发症均有不同程度缓解。结论胃旁路术能有效治疗2型糖尿病,手术安全可行,近期效果明显,长期效果仍待观察。
The single center clinical experiences of laparoscopic Roux-en-Y gastric bypass surgery for treatment of type 2 diabetes mellitus
Objective To evaluate the surgical approach and effectiveness of laparoscopic Roux-en-Y gastric bypass(LRYGB) surgery for treating type 2 diabetes mellitus. Method To analyze 20 patients' data with laparoscopic Roux-en-Y gastric bypass surgery for treatment of type 2 diabetes mellitus from August 2010 to February 2012. Result The blood glucose of 20 patients were reduced significantly.Glucose tolerance enhanced(P<0.05). The body mass of 12 patients were changed significantly. 15 patients were visited from 3 month to 12 month, the blood glucose in normal range without taking up insulin or medications. The cases of 4 patients were visited for 6 months, HOMA-IR, HbAlc compared with preoperative significantly reduced(P<0.05); Diabetes-related complications have varying degrees of relief. Conclusion LRYGB surgery is feasible for treatment of type 2 diabetes with good short-term result, but the long-term outcome awaits further observation.

Laparoscopy gastric bypass surgeryType 2 diabetes mellitus

张进峰、周宏建、张光辉、王存川、张春明、苏楠、李炎萍、郭励

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453000 河南省郑州市第二人民医院普外科

腹腔镜胃旁路术 2型糖尿病

2011年郑州市科技发展项目

2013

中国医疗前沿
中国医院协会

中国医疗前沿

影响因子:0.186
ISSN:1673-5552
年,卷(期):2013.(15)
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