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洛伐他汀联合复方丹参滴丸治疗高血脂合并冠心病的临床疗效

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目的观察洛伐他汀联合复方丹参滴丸治疗高血脂合并冠心病的临床疗效。方法将2011年3月-2012年9月我院冠心病合并高血脂患者80例随机分为两组各40例。在常规治疗的基础上,对照组给予洛伐他汀治疗,治疗组给予洛伐他汀联合复方丹参滴丸治疗,观察治疗后两组患者心绞痛、ECG情况,TC、LDL-C指标,比较两组疗效。结果治疗组患者心绞痛疗效有效率、ECG有效率高于对照组,差异有统计学意义(P<0.05);两组治疗后血脂水平均较治疗前显著降低,差异有统计学意义(P<0.05),组间血脂水平差异不大(P>0.05)。结论洛伐他汀联合复方丹参滴丸治疗高血脂合并冠心病疗效满意,值得临床推广。
Objective To observe the curative effects of lovastatin combined with compound Danshen dripping pills in the treatment of coronary heart disease combined with hyperlipemia. Methods Select 80 patients from March 2011 to September 2012 who were diagnosed with coronary heart disease combined with hyperlipemia, randomly divide them into treatment group and control group ,each of the team had 40 patients. the patients in control group were treated with lovastatin, and the treatment group were treated with lovastatin combined with compound Danshen dripping pills, observe their times of stenocardia happen times and changes of ECG after 30 weeks' treatment, test their TC,LDL-C level in blood, compare the therapeutic effect of two groups. Results The angina remission rate of treatment groups was 87.5%, while the angina remission rate of control groups was 60.0%. It had significant difference between two groups(P<0.05); and the ECG remission rate of treatment groups was 72.5%, while the ECG remission rate of control groups was 42.5%. It had significant difference between two groups(P<0.05). After 30 weeks' treatment, blood lipid level of both two groups were significantly decreased than before, however there was no significant difference between two groups after 30 weeks' treatment. Conclusion The clinical effect of lovastatin combined with compound Danshen dripping pills in the treatment of coronary heart disease combined with hyperlipemia is satisfied.it is worth clinical application.

LovastatinCompound Danshen dripping pillsCoronary heart disease combined with hyperlipemia

张英

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430015 武汉,江汉大学附属医院第六医院西药剂科

洛伐他汀 复方丹参滴丸 高血脂 冠心病

2013

中国医疗前沿
中国医院协会

中国医疗前沿

影响因子:0.186
ISSN:1673-5552
年,卷(期):2013.(16)
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