Comparison of therapeutic effects of pitavastatin and pravastatin after acute myocardial infarction
Objective This analysis compared the efficacy of pitavastatin to pravastatin in post-acute myocardial infarction patients. Methods 120 of acute myocardial infarction patients were randomly divided into two groups which were received pitavastatin(2mg/d) and pravastatin(10mg/d), After 12 months of follow-up visit, LDL was measured and coronary artery disease,myocardial infarction and acute coronary syndromewere observed. Results There was no difference in baseline LDL-C concentrations between the 2 groups. Although LDL-C was decreased more potently in the pitavastatin than pravastatin groups, acute coronary syndrome events tended to occur less frequently in the pravastatin than pitavastatin groups. Conclusion In Chinese patients after acute myocardial infarction, pitavastatin provided significantly greater LDL-C and TC reductions from base-line to 12 months, but pravastatin could be superior to lipophilic statins at reducing cardiovascular events.
NETL
NSTL
万方数据
维普
