Expression and clinical significance of MMP-9 in endometrial adenocarcinoma
Objective To investigate expression and clinical significance of MMP-9 in endometrial adenocarcinoma. Method 30 cases were diagnosed as endometrial adenocarcinoma tumor tissue after a routine pathological diagnosis, 25 cases of normal endometrial tissue in control group underwent hysterectomy due to benign lesion in ovaries and fallopian tubes from November 2011 to December 2012.mRNA expression of MMP-9was determined by RT-PCR in endometrial adenocarcinoma. Results The positive rate of MMP-9 in endometrial adenocarcinoma was signicantly higher than those in control group. Comparsion of the different clinical stage groups was statistically significant. Statistical significance was also found in pathological grade groups. Conclusion MMP-9 expression is closely related to the clinical stage and pathological grade in endometrial adenocarcinoma.
NETL
NSTL
万方数据
维普
