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血必净对严重腹腔感染患者肠道功能及炎症反应的影响

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目的:探讨血必净对严重腹腔感染患者肠道功能及炎症反应的影响。方法将我院2008年1月-2013年5月严重腹腔感染患者60例随机均分为对照组(常规治疗)和实验组(常规治疗基础上给予血必净注射液)各30例,比较两组患者治疗前后血浆DAO、LPS、TNF-α、IL-6水平及氧合指数(OI)、APACHE-II评分。结果经5d治疗后,实验组血浆DAO、LPS、TNF-α、IL-6水平明显低于对照组(P<0.05),氧合指数明显高于对照组(P<0.05),APACHE-II评分明显低于对照组(P<0.05)。结论血必净注射液对改善严重腹腔感染患者的肠道功能及炎症反应效果显著,并能有效减少内毒素入血,值得临床推广。
The effect of Xue Bi Jing on the intestinal function and inflammation in parents with severe abdominal infection
Objective To investigate the effect of Xue Bi Jing on the intestinal function and inflammation in parents with severe abdominal infection.Methods 60 cases patients with severe abdominal infection in our hospital from January 2008 to March 2013 were divided into Control group(conventional therapy) and Experimental group(conventional therapy and given Xue Bi Jing), the DAO, LPS, TNF-α, IL-6 levels in plasma and oxygenation index(OI), APACHE-II score of two groups before and after treatment were compared. Results The DAO, LPS, TNF-α, IL-6 levels in plasma of Experimental group were lower than that of Control group(P<0.05), the OI in Experimental group was higher that in Control group(P<0.05), the APACHE-II score of Experimental group was lower than that of Control group(P<0.05). Conclusion Xue Bi Jing has a significant effects on improving the intestinal function and inflammation in in parents with severe abdominal infection, and it can reduce endotoxin into the blood,which was worthy of clinical widely.

Xue Bi JingSevere abdominal infectionIntestinal functionInflammation

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215600 江苏省张家港市第一人民医院ICU

血必净 严重腹腔感染 肠道功能 炎症反应

2013

中国医疗前沿
中国医院协会

中国医疗前沿

影响因子:0.186
ISSN:1673-5552
年,卷(期):2013.(17)
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