摘要
目的：探讨大剂量甲基泼尼松龙治疗急性外伤性脑水肿的效果。方法将80例急性外伤性脑水肿患者随机分为两组各40例，对照组应用常规综合治疗，包括止血、脱水、利尿、抗感染、钙拮抗、神经营养等，研究组在此基础上加用甲基泼尼松龙，对比两组疗效。结果研究组患者脑水肿Ⅰ度比例明显高于对照组，Ⅲ度明显低于对照组；研究组患者恢复良好率明显高于对照组，死亡率明显低于对照组(P<0.05)。结论大剂量甲基泼尼松龙治疗急性外伤性脑水肿具有较好抗炎作用和临床疗效，可有效改善脑水肿。
Abstract
Objective To explore the effect of high-dose methylprednisolone for acute traumatic brain edema. Methods 80 cases of acute traumatic brain edema were randomized: Control group of 40 patients were treated with conventional therapy, including bleeding, dehydration, diuretic, anti-infection, calcium antagonists, neural nutrition; Based on the treatment methods of the control group, the study group of 40 patients were plus methyl prednisolone, the treatment effect of two groups was compared. Results After treatment, I degree of cerebral edema of the study group was significantly higher the control group, Ⅲ degree was significantly lower than the control group; The rate of good recovery of the study group was significantly higher the control group, mortality rate was significantly lower than the control group(P<0.05). Conclusion High-dose methylprednisolone treatment of acute traumatic brain edema has good anti-inflammatory effects and clinical efficacy, can effectively improve cerebral edema.
NETL
NSTL
维普
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