首页|尿毒清颗粒治疗慢性肾衰竭的临床应用研究

尿毒清颗粒治疗慢性肾衰竭的临床应用研究

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目的:探讨尿毒清颗粒对慢性肾衰竭患者24h尿蛋白定量、肾功能、血脂及微炎症状态的疗效。方法169例确诊为慢性肾衰竭的患者随机分为对照组、药用炭片组、尿毒清颗粒组。对照组给予常规治疗,药用炭片组及尿毒清组在常规治疗基础上加用药用炭片或尿毒清颗粒,疗程8周。结果尿毒清颗粒显著改善慢性肾衰竭患者尿蛋白、肾功能、血脂及微炎症状态,与对照组、药用炭片组比较,差异有统计学意义(P<0.05)。药用炭片显著改善患者肾功能,对尿蛋白、血脂、微炎症状态无治疗作用。结论尿毒清颗粒通过减少蛋白尿、改善脂类紊乱、抑制微炎症状态,发挥改善患者肾功能及减少心血管事件、贫血、营养不良等并发症的作用。
Clinical Application of Uremic Clearance Granules In Chronic Renal Failure
Objective To investigate the efficiency of Uremic Clearance Granules on Chronic Renal Failure for 24h urinary protein excretion, renal function, blood fat and micro-inflammation state. Methods 169 patients with Chronic Renal Failure were randomly divided into control group, Medicinal Charcoal Tablets group and Uremic Clearance Granules group. Control group were given routine therapy alone, Medicinal Charcoal Tablets group were given routine therapy and Medicinal Charcoal Tablets, Uremic Clearance Granules group were given routine therapy and Uremic Clearance Granules, treatments were maintained for 8 weeks. Results Compared with control group and Medicinal Charcoal Tablets group, levels of 24h urinary protein excretion, renal function、blood fat and micro-inflammation state obviously decreased in Uremic Clearance Granules group after therapy(P<0.05). Compared with control group, levels of renal function obviously decreased, levels of 24h urinary protein excretion, blood fat and micro-inflammation state did not changed in Medicinal Charcoal Tablets group after therapy. Conclusion By means of decreasing levels of 24h urinary protein excretion、blood fat and micro-inflammation state, Uremic Clearance Granules can improve renal function and decrease probability of cardiovascular event、anaemia and malnourish.

Uremic Clearance GranulesChronic Renal Failure24h urinary protein excretionRenal functionBlood fatMicro-inflammation state

郭敏、郭伟杰、杜跃亮、蔡沛武

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462000 漯河医学高等专科学校一附院/河南省漯河市中心医院肾内科

462000 漯河医学高等专科学校一附院检验科

尿毒清颗粒 慢性肾衰竭 24h尿蛋白定量 肾功能 血脂 微炎症状态

2013

中国医疗前沿
中国医院协会

中国医疗前沿

影响因子:0.186
ISSN:1673-5552
年,卷(期):2013.(17)
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