手术联合5-氨基酮戊酸光动力疗法治疗鳞状细胞癌和日光性角化病临床疗效分析
Clinical Efficiency of Surgical Operation and ALA-PDT in the Treatment of Squamous Cell Carcinoma and Actinic Keratosis
郑渊 1董达科 1翟建新 1蒋屏东 1戚稼 1杨莉佳1
作者信息
- 1. 214000 南京医科大学附属无锡二院皮肤科
- 折叠
摘要
目的：分析手术联合5-氨基酮戊酸光动力疗法(ALA-PDT)治疗鳞状细胞癌(SCC)和日光性角化病(AK)的疗效。方法对34例患者皮损采取手术切除，于术后第2d开始ALA-PDT，每周1次，共3-7次，随访15-36月。结果所有患者治疗结束后均为完全反应(完全反应率100%)，随访仅1例SCC患者复发(复发率5.26%)，AK患者无复发。结论手术联合ALA-PDT治疗SCC和AK有效、安全。
Abstract
Objective To analyse the clinical efficiency of surgical operation and 5-aminolevulinic acid photodynamic therapy(ALA-PDT) in the treatment of squamous cell carcinoma(SCC) and actinic keratosis(AK). Methods 34 patients were received surgical operation, then 3-7 times of ALA-PDT (once a week from the next day after operation), and then follow-up of 15-36 months. Results All patients responded completely(100% of total cases), and in follow-up only one patient of SCC recurred(5.26% of 19 cases); no patients of AK recurred. Conclusion Treating SCC and AK with combination of surgical operation and ALA-PDT is one of the effective and safe methods.
关键词
鳞状细胞癌/日光性角化病/手术/5-氨基酮戊酸光动力疗法/疗效Key words
Squamous cell carcinoma/Actinic keratosis/Surgical operation/ALA-PDT/Clinical efficiency引用本文复制引用
出版年
2013
NETL
NSTL
维普
万方数据