Relationship between serum adiponectin and resistin in old patients with obstructive sleep apnea syndrome with insulin resistance
Objective To study the changes of Serllm adiponectin and resistin levels in old patients with OSAS and the relationship of adiponeetin and resistin with insulin resistance(IR). Methods Using two matched case-control study, choose the weight, age, quite in elderly patients with OSAS 50 cases as a group, in addition to choose simple snoring group 35 cases as a contrast, using multiple guide apparatus to monitor the sleep, and use the radiation immunoassay, enzyme-linked immune method to determine the object of study of serum lipid even element, resistin level. By using the steady state model method(HOMA) index calculation of IR. Results Cases of serum lipid levels lower than the control group, and triglyceride levels, fasting insulin(FINS), HOMA IR, resistin levels were higher than the control group. After Logistic multivariate regression analysis showed that glycemic index, body mass index, apnea hypoventilation index, grease even element, resistin are independent risk factors of insulin resistance in patients with OSAS. Conclusion OSAS patients further related to fat even element, resistin, and for the development of insulin resistance may be with fasting blood glucose, fasting insulin, body mass index, apnea ventilation index have relations. By controlling the above indicators may reduce the risk of OSAS patients complicated with IR.
Obstructive sleep apnea syndromeInsulin resistanceSerum adiponectinState model method
NETL
NSTL
万方数据
维普
