Comparison of effects of Dezocine and Sufentanil on reducing visceral traction in hysterectomy
Objective To investigate the prevention effects of intravenous dezocine and sufentanil on visceral traction reaction during hysterectomy under the spinal-epidural anesthesia. Methods Sixty ASAⅠ -Ⅱpatients, scheduled for hysterectomy under the spinal-epidural anesthesia, were randomly divided into three groups(n=20): sufentanil 10μg(S group), dezocine 5mg(D1 group) and dezocine 10mg(D2 group). MAP, HR, SpO2, Ramsay sedation score, VAS pain score and visceral traction reaction were recorded separately at different time points as follows: Baseline(T1), before administration(T2), 15 minutes after administration(T3), to open the peritoneum(T4), when the uterus probe(T5), breaking the uterine ligaments(T6), wipe the abdominal cavity(T7). Results S group and D2 group of patients with relatively normal circumstances, Ramsay score, VAS score, MAP, HR,and SPO2 was no significant difference(P>0.05), D1 group visceral reaction score higher than S and D2 group(P<0.05). Conclusion Dezocine 10 mg IV is as effective as sufentanil in preventing visceral reaction during hysterectomy, with less incidence of nausea, vomiting and respiratory depression.