A clinical observation on metadoxine combined with magnesium isoglycyrrhizinate in the treatment of patients with alcoholic liver disease
Objective To evaluate the efficiency of metadoxine combined with tiopronin in the treatment of patients with alcoholic liver disease. Methods 72 cases of hospitalized patients with alcoholic liver disease were randomly divided into treatment group and control group with 35 cases in one group, 37 cases in another group, The two groups received the same general treatment, and the control group was treated with metadoxine, while the treatment group was added with metadoxine tablets based on the treatment of the control group. The TBil, ALT, AST, GGT, and other biochemical indices were detected before and after treatment respectively, and the clinical symptoms and signs were observed. Results After 4 weeks, the total treatment efficiency in treatment group was significantly higher than that in control group; after treatment the TBil, ALT, AST, GGT levels were significantly lower in treatment group than those in the control group, the difference was statistically significant(P<0.01). Conclusion Metadoxine and magnesium isoglycyrrhizinate combined treatment shows better effect than the single treatment with metadoxine.
NETL
NSTL
万方数据
维普
