Objective To explore the effects and clinical value of Xuebijing injection and Ulinastatin injection on severe infection and sepsis of patients with critical type multiple trauma. Methods 70 patients of critical type multiple trauma were randomly divided into two groups: treatment group(35 cases) and control group(35 cases). Clinical effects were observed, and the hepatic and renal functions, IL-1β, IL-6, TNF-α, PCT and hs-CRP. Results After treatment of 48 hours and 120 hours, the serum levels of IL-6, TNF-α, PCT and hs-CRP were reduced significantly in two groups(P<0.05); the degree of reduction were more significant in treatment groups than those in control groups (P<0.05). Conclusion The application of Xuebijing injection and Ulinastatin injection could significantly improve the inflammatory response in patients with critical type multiple trauma.
Critical type multiple traumaXuebijing injuctionUlinastatinSystemic inflammatory response syndromeSepsis