Evaluation of internal carotid artery lesions in combination with carotid contrast-enhanced ultrasound and transcranial Doppler in patients with posterior circulation ischemia
Objective To evaluate internal carotid artery lesions in patients with posterior circulation ischemia(PCI) with carotid contrast-enhanced ultrasound(CEUS) and transcranial Doppler(TCD). Method A total of 125 patients with PCI were divided into an infarction group(n=52) and a transient ischemia attack(TIA) group(n=73). They were all underwent carotid CEUS and TCD examination. Fifty-four healthy subjects were selected as control group. The plaque characteristics and stenosis of extracranial internal carotid artery of the infarction group and TIA group were compared. The stenosis of extracranial internal carotid artery and its effect on hemodynamics of posterior circulation artery were evaluated. Results ①Among the plaque detected from extracranial internal carotid artery, the vulnerable plaque was 66.3%(61/92) in cerebral infarction group. It was significantly higher than 39.7%(29/73) in the TIA group. There was statistical significance(P <0.01). ②The occurrence of vulnerable plaque was 65.4%(34/52) in the infarction group. It was significantly higher than 42.5%(31/73) in the TIA group. There was statistical significance (P <0.05).③The incidence of ≥50% stenosis of extracranial internal carotid artery in the infarction group was 32.7%(17/52). It was higher than 16.4%(12/73) in the TIA group. There was statistical significance(P <0.05). ④The peak velocity of posterior cerebral artery P1 segment, basilar artery and intracranial vertebral artery were significantly higher than that in control group(P <0.05) in 11 anterior circulation steal patients. Conclusion CEUS combined with TCD can help to evaluate internal carotid artery atherosclerostic lesions, identify the vulnerable plaque, appraise hemodynamics of anterior and posterior circulation artery in patients with PCI.
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维普
