Comparative studies on the distribution of Ephedrine in Ephedra traditional powder and ultra-micro powder in the heart of mice
Objective Comparative studies on the distribution of Ephedrine in Ephedra ultra-micro powder and traditional powder in the heart of mice,and discuss the changes on distribution affected by different particle size of Ephedra. Methods The mices were randomized into two groups, one was supplied with ultra-micro powder and the other was administrated with traditional powder. The distributions of Ephedrine in mice hearts were analysed by HPLC method. Results At various time points, the concentration of ultra-micro powder was higher than traditional powder, and particularly significantat at 8h. Conclusion The ultra-micro powder can increase the concentration of ephedrine in the heart of mice.