Effect of Tiotropium combined pulmonary rehabilition on pulmonary hypertension and quality of life for patients with chronic obstructive pulmonary disease in stable phase
Objective To observe effect of tiotropium combined pulmonary rehabilition on patients of stable chronic obstructive pulmonary disease complicated with pulmonary hypertention. Methods A total of 71 patients of pulmonary function inⅡ-Ⅲ stable COPD complicated with pulmonary hypertension were recruited. The were divided into observation group(n=35) and control group(n=36), the patients in control group received pulmonary rehabilitation measures, the observation group in addition to receiving tiotropium inhalation, after 6 months of intervention. Comparing the two group of patients with 6min walking distance, the systolic pulmonary artery pressure and quality of life. Results The distance of 6min walk, the systolic pulmonary artery pressure and quality of life in the observation group than the control group, the difference was statistically significant(P <0.01). Conclusion For patients of stable COPD complicated with pulmonary hypertension, inhaled tiotropium dry power combined with pulmonary rehabilitaton, can reduce pulmonary artery systolic pressure, improve the symptoms of the disease, improve the quality of life.
TiotropiumpulmonaryDiseaseChronic obstructiveBlood pressurePulmonary arteryRehibilationQuality of life
NETL
NSTL
万方数据
维普
