The clinical research of perimenopausal women with Hashimoto's thyroiditis of estrogen level
Objective To observe the perimenopausal patients with Hashimoto's thyroiditis estradiol changes and explore its significance. Methods 32 female perimenopausal patients with Hashimoto's thyroiditis, 32 perimenopausal women volunteers, detect the level of estradiol after 13 days of the period. Detection of three thyroid function parameters, anti-thyroid autoantibodies parameters for the diagnosis of Hashimoto's thyroiditis. Results The estradiol level of perimenopause Hashimoto's thyroiditis patients is 284.47±82.17ng/L, and the control group is 169.62±61.05ng/L, which is a significant difference. TGAb and E2 levels were positively correlated(r=0.519, P <0.05). Conclusion The perimenopausal patients with Hashimoto's thyroiditis elevated estradiol levels compared to the control group, suggesting that estrogen may in perimenopausal women Hashimoto's thyroiditis play a role in the pathogenesis.
NETL
NSTL
万方数据
维普
