Value of monitoring the level of ADA, CEA and CA19-9 in the differential diagnosis of benign and malignant pleural effusions
Objective To investigate the ADA, CEA and CA19-9 indicators of significance and diagnostic value for differentiating the benign and malignant pleural effusions. Method Collected 118 cases of patients with pleural effusions treated in our hospital, and divided into the benign group and the malignant group. Compared the results of ADA, CEA and CA19-9 between two groups. Results Malignancy tumor markers CEA and CA19-9 level of the malignant group were significantly higher than those in the benign group, while ADA level were significantly lower than that in the benign group, with statistically significant difference(P <0.05). And joint detection can significantly improve the diagnostic sensitivity(98.31%). Conclusion The joint detection of ADA, CEA and CA19-9 have important diagnostic significance and clinical value in differentiating the benign and malignant pleural effusions.