Early recanalization of the infarct related artery thrombolytic therapy on left ventricular function prognosis in patients with acute myocardial infarction
Objective To evaluate the effect of early recanalization of the infarct related artery thrombolytic therapy on left ventricular function and BNP level in patients with acute myocardial infarction. Methods 92 patients with acute myocardial infarction were divided into control and observation group randomly, with 46 patients in each group, the onset time of all the patients were within 12h, and all were the first onset. Patients in control group were given conventional treatment, and patients in observation group were given early recanalization of the infarct related artery thrombolytic therapy. Plasma BNP level of all the patients were tested on admission and 1 week after onset, left ventricular remodeling and left ventricular function were recorded and analyzed by echocardiography,And carries on the comparison to the incidence of adverse events. Results Plasma BNP level in observation group were lower than in control group significantly(P <0.05). The left ventricular function situation in observation group was better than in control group significantly(P <0.05). Observation group, incidence of adverse events was significantly lower than the control group(P <0.05). Conclusion Early recanalization of the infarct related artery thrombolytic therapy reduced plasma BNP concentration and has a certain inhibitory action on the left ventricular remodeling, it improves left heart function situation effectively leading to low incidence of adverse cardiac events in patients with acute myocardial infarction.
Acute myocardial infarctionInfarct related arteryBNPThrombolytic therapyLeft ventricular remodeling
NETL
NSTL
万方数据
维普
