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慢性阻塞性肺病患者呼吸肌力的恢复与维生素C、E及血清瘦素的关系

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目的:探讨慢性阻塞性肺病(COPD)患者呼吸肌力恢复同维生素C、E及血清瘦素的关系。方法将45例病情稳定的COPD患者随机分为维生素治疗组25例和呼吸康复训练组20例,常规药物治疗基础上,维生素组每日于饮食中适量添加维生素C、E。另外选择20例健康志愿者作为对照组,经30d治疗后分别测定各组维生素C、E,肺通气功能、呼吸肌力、呼吸中枢驱动功能等指标。结果治疗前患者组的维生素C、E水平显著低于对照组。治疗后,维生素组呼吸肌力相比康复训练组恢复佳,维生素C、E水平显著高于康复训练组(P <0.05)。此外,血清瘦素与最大吸气压正相关(r=0.153)。结论血清维生素C、E同COPD患者呼吸肌力恢复相关,提高患者的维生素C、E水平可加速COPD患者呼吸肌力恢复,血清瘦素同呼吸肌力也具有一定相关性。
Chronic obstructive pulmonary disease patients breathing muscle recovery and vitamin D, E relationship
Objective To study the chronic obstructive pulmonary disease patients breathing muscle recovery with vitamin C, E correlation. Methods Choice 45 patients in stable condition of chronic obstructive pulmonary disease patients as the research object, the case group will be in accordance with the principle of randomized divided into vitamin treatment group, and respiratory rehabilitation training. Two groups of patients were accepted routine drug therapy, vitamin group in rehabilitation training at the same time in the daily diet right amount add vitamin C, E. Choose another 20 cases without history of smoking healthy volunteers as control, after 30 days after treatment, respectively the observation object vitamin C, E, pulmonary ventilation function, respiratory muscle strength, respiratory center drive function and arterial blood gas index, etc. Line correlation analysis. Results Before treatment in a group of patients with vitamin C, E were significantly lower than those of the control group. After treatment, vitamin group of respiratory muscle strength of rehabilitation training compared to restore good, vitamin C, E were significantly higher than that of treatment of rehabilitation training. Conclusion Serum vitamin C, E COPD patients with respiratory muscle recovery related, improve the patients of vitamin C, E level can be accelerated COPD patients with respiratory muscle recovery, which have the important instruction significance for clinical.

COPDRespiratory muscle strengthVitamin CVitamin EBlood leptin

龙竹青

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663100 云南省文山州砚山县中医医院

慢性阻塞性肺病 呼吸肌力 维生素C 维生素E 血清瘦素

2013

中国医疗前沿
中国医院协会

中国医疗前沿

影响因子:0.186
ISSN:1673-5552
年,卷(期):2013.(21)
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