Clinical Study of interventional chemotherapy and intravesical instillation for preventing recurrence of su-perficial bladder cancer
Objective To study the therapeutic efficacy of combined interventional chemotherapy and in-travesical instillation of pirarubicin on preventing bladder cancers from recurring after local ablation. Methods 32 patients with superficial bladder cancers were randomized into combined interventional chemotherapy and intrav-esical instillation of pirarubicin or intravesical instillation of pirarubicin alone for preventing recurrence after local ab-lation. Results The patients have been followed up for 12-28 months. 1 case has had tumor recurrence in the combined modality therapy group and 5 in the intravesical instillation alone group,the tumor recurrence rate being 6%(1/16) and 31%(5/16) respectively(P <0.05). Conclusions Combined use of interventional chemotherapy and intravesical instillation of pirarubicin is effective in preventing superficial bladder cancer from recurring after local ablation with fewer adverse effects. The ragimen is not only reliable but also safe.
NETL
NSTL
万方数据
维普
