Study on cardiac function classification or different etiology on neuroendocrine levels and heart function in patients with chronic heart failure
Objective To explore the effect of cardiac function classification or different etiology on neuroendocrine levels and heart function in patients with chronic heart failure. Methods 168 patients with chronic heart failure of tour hospital were divided into group A(72 cases, grade Ⅲ) and B(96 cases, grade Ⅳ) according to cardiac function classification, and were divided into groupⅠ(coronary), Ⅱ(dilated cardiomyopathy) and Ⅲ (hypertension) according to basic etiology. PRA, AngⅡ, ALD, BNP, LVEDD, LVEF of different etiology and cardiac function classification were compared and analyzed. Results Level of PRA, AngⅡ, ALD, BNP, LVEDD and LVEF of group B were higher than group A significantly(P <0.05). Level of PRA, AngⅡ, ALD, BNP, LVEDD and LVEF among group Ⅰ, Ⅱand Ⅲ were not significant(P >0.05). Conclusion The worse of cardiac function, the more obviously of neuroendocrine levels were activated, the phenomenon promotes the release of PRA, AngⅡ, ALD and BNP, adding to ventricular remodeling.
NETL
NSTL
万方数据
维普
