中国有色金属学报(英文版)2024,Vol.34Issue(9) :2814-2827.DOI:10.1016/S1003-6326(24)66578-7

可生物降解镁锌银非晶的设计与表征

Design and characterization of biodegradable Mg-Zn-Ag metallic glasses

王见 王晨 饶伟峰 In-ho JUNG
中国有色金属学报(英文版)2024,Vol.34Issue(9) :2814-2827.DOI:10.1016/S1003-6326(24)66578-7

可生物降解镁锌银非晶的设计与表征

Design and characterization of biodegradable Mg-Zn-Ag metallic glasses

王见 1王晨 2饶伟峰 3In-ho JUNG4
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作者信息

  • 1. 扬州大学机械工程学院,扬州 225009;Department of Materials Science and Engineering,Seoul National University,Seoul 08826,Korea
  • 2. 扬州大学机械工程学院,扬州 225009
  • 3. 齐鲁工业大学机械与汽车工程学院,济南 250353
  • 4. Department of Materials Science and Engineering,Seoul National University,Seoul 08826,Korea
  • 折叠

摘要

为了开发用于生物可降解植入物的镁锌银非晶,采用相图计算(CALPHAD)和实验测量相结合的方法研究镁锌银合金的非晶成形能力(GFA)和生物相容性.对Mg96-xZnxAg4和Mg94-xZnxAg6(x=17,20,20,23,26,29,32,35)两种合金系列的高GFA潜力进行理论预测,并通过实验测试进行证实.采用X射线衍射(XRD)和差示扫描量热法(DSC)评价这些合金的结晶度、GFA值和结晶特性.根据目前的结果,成分介于Mg73Zn23Ag4和Mg64Zn32Ag4之间的Mg96-xZnxAg4系列合金以及成分介于Mg66Zn28Ag6和Mg63Zn31Ag6的Mg94-xZnxAg6系列合金具有良好的GFA.值得注意的是,Mg96-xZnxAg4系列的GFA优于Mg94-xZnxAg6系列.此外,合金Mg70Zn26Ag4、Mg74Zn20Ag6和Mg71Zn23Ag6具有可接受的腐蚀速率和细胞相容性,对细胞增殖有积极作用.这些特性使它们适合应用于医疗环境中,有可能作为可生物降解植入物的材料.

Abstract

In order to develop the Mg-Zn-Ag metallic glasses(MGs)for biodegradable implant applications,the glass formation ability(GFA)and biocompatibility of Mg-Zn-Ag alloys were investigated using a combination of the calculation of phase diagrams(CALPHAD)and experimental measurements.High GFA potentiality of two alloy series,specifically Mg96-xZnxAg4 and Mg94-xZnxAg6(x=17,20,23,26,29,32,35),was predicted theoretically and then substantiated through experimental testing.X-ray diffraction(XRD)and differential scanning calorimetry(DSC)techniques were used to evaluate the crystallinity,GFA,and crystallization characteristics of these alloys.The results showed that compositions between Mg73Zn23Ag4 and Mg64Zn32Ag4 for Mg96-xZnxAg4,Mg66Zn28Ag6 and Mg63Zn31Ag6 for Mg94-xZnxAg6 displayed a superior GFA.Notably,the GFA of the Mg96-xZnxAg4 series was better than that of the Mg94-xZnxAg6 series.Furthermore,the Mg70Zn26Ag4,Mg74Zn20Ag6,and Mg71Zn23Ag6 alloys showed acceptable corrosion rates,good cytocompatibility,and positive effects on cell proliferation.These characteristics make them suitable for applications in medical settings,potentially materials as biodegradable implants.

关键词

非晶成形能力/相图计算/镁锌银非晶/细胞相容性

Key words

glass forming ability/calculation phase diagram(CALPHAD)/Mg-Zn-Ag metallic glasses/cytocompatibility

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基金项目

Shenzhen Basic Research Project,China(JCYJ20170815153210359)

National Natural Science Foundation of China(12174210)

出版年

2024
中国有色金属学报(英文版)
中国有色金属学会

中国有色金属学报(英文版)

CSTPCDCSCD
影响因子:1.183
ISSN:1003-6326
参考文献量9
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