紫草油搽剂的制备工艺及质量评价
Preparation Technology and Quality Evaluation of Comfrey Oil Liniment
吴韵 1吴俊 1何频 1洪仕奎 1马丽娟 1夏开梅 1成雪1
作者信息
- 1. 毕节市中医医院药学科制剂中心,贵州毕节 551700
- 折叠
摘要
目的 优化紫草油搽剂的制备工艺,并对其质量进行评价.方法 在单因素试验的基础上,以浸泡时间、药材粉碎度、提取次数为考察因素,羟基萘醌总色素的含量为评价指标,采用正交设计试验对紫草油搽剂的制备工艺进行优化.结果 紫草油搽剂的最佳制备工艺为 225 ml山茶油浸泡原药材,浸泡两次,共浸泡 5 d;紫草油搽剂均匀、稳定,3 批样品中羟基萘醌总色素平均含量为 61.17 mg/g.结论 优化的紫草油搽剂制备工艺简单可行,易操作,制得的紫草油搽剂质量均匀、稳定,可为下一步研究奠定基础.
Abstract
Objective To optimize the preparation process of comfrey oil liniment and evaluate its quality.Methods On the basis of single factor experiment,with soaking time,crushing Degree and extraction times as factors and the content of total pigment of hydroxyl naphthoquinone as evaluation index,orthogonal design experiment was used to optimize the preparation technology of liniment of compost oil.Results The best preparation process of linimentum of comya oil was 225mL camellia oil soaked in the original medicinal material for 2 times for a total soaking time of 5 d.The liniment was uniform and stable,and the total pigment content of hydroxynaphthoquinone in 3 batches of samples was 61.17mg/g.Conclusion The optimized preparation process of linimentum comfrey oil is simple,feasible,easy to operate,uniform and stable in quality,which can lay a foundation for further research.
关键词
紫草油/搽剂/制备工艺/质量评价Key words
Comfrey oil/Linimentum/Preparation process/Quality evaluation引用本文复制引用
基金项目
毕节市联合基金项目(毕科联合字Z[2018]8号)
出版年
2024
国家科技期刊平台
NSTL
万方数据