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胶质瘤的免疫微环境及免疫治疗的研究进展

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胶质瘤是中枢神经系统最常见的恶性肿瘤之一,对人类健康造成了严重威胁。深入了解胶质瘤的发病机制,分析影响胶质瘤发展的可能因素,以及探索新型治疗方案对改善胶质瘤进展和预后至关重要。目前研究发现,肿瘤免疫微环境中免疫细胞浸润、免疫检查点分子等与胶质瘤的发生发展密切相关。本文就胶质瘤免疫微环境中常见的相关肿瘤免疫细胞及其逃逸机制,以及免疫治疗领域研究进展进行综述。
Research Progress of Immune Microenvironment and Immunotherapy in Glioma
Glioma is one of the most common malignant tumors of the central nervous system,posing a serious threat to human health.A comprehensive understanding of the pathogenesis of glioma,analysis of potential factors influencing its development,and exploration of novel treatment strategies are crucial for improving its progression and prognosis.Current research has revealed that immune cell infiltration and immune checkpoint molecules in the tumor immune microenvironment are closely associated with the occurrence and progression of giloma.This article provides a review of the common tumor immune cells and their evasion mechanisms in the immune microenvironment of giloma,as well as the research progress in the field of immunotherapy.

GliomaImmune microenvironmentImmune evasionImmunotherapy

韩澳迎、王立康、曹艳菲、张丽娜

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佳木斯大学临床医学院,黑龙江 佳木斯 154007

大庆市大庆油田总医院检验科,黑龙江 大庆 163001

胶质瘤 免疫微环境 免疫逃逸 免疫治疗

2024

中国药物经济学
中国中医药研究促进会

中国药物经济学

影响因子:0.712
ISSN:1673-5846
年,卷(期):2024.19(11)