Rational evaluation of prophylactic use of antibiotics in orthopedic joint replacement based on attribute hierarchical model
Objective To explore the rational evaluation criteria for the prophylactic use of antibiotics in orthopedic joint replacement(including knee replacement and hip replacement)based on the attribute hierarchical model(AHM)to provide a reference for the prophylactic use of antibiotics in this surgery.Methods According to the Guidelines of Clinical Use of Antimicrobial Agents(2015 edition),the Sanford Guide to Antimicrobial Therapy(48th edition),relevant drug instructions and treatment guidelines at home and abroad,the reasonable evaluation criteria for the prophylactic use of antibiotics in joint replacement based on AHM was developed.The perioperative use of antibiotics in 208 patients undergoing joint replacement from January 2021 to December 2021 in Anqing Medical Center of Anhui Medical University was analyzed accordingly.Results The main unreasonable types and proportions of prophylactic use of antibiotics in orthopedic joint replacement were cephalosporin skin test(65.87%),course of medication(61.06%),dosage(53.37%)and drug selection(26.92%).Of all the patients,41(19.71%)had a medical record score(MRS)≥90,67(32.21%)had a score of 80≤MRS<90,87(41.83%)had a score of 60≤MRS<80 and 13(6.25%)had a MRS<60.Conclusion The perioperative use of antibacterial drugs during orthopedic joint replacement in Anqing Medical Center of Anhui Medical University is relatively reasonable,but there is unreasonable medication need to be further standardized in terms of drug selection,dosage,course of medication and cephalosporin skin test.
Attribute hierarchical modelJoint replacementProphylactic use of antibioticsRational evaluation