Objective To investigate the effectiveness and feasibility of pharmacists'application of the PDCA management method for the standardized management of psychotropic drug prescriptions.Methods The prescriptions of 639 patients who were prescribed to receive treatment with psychotropic drugs in Yuncheng Central Hospital from January to December in 2022 were selected as the study subjects and divided into the conventional management group(n=354)and the PDCA management group(n=285)based on the prescription data before and after the implementation of the PDCA management method.The conventional management mode was used in the conventional management group from January to June in 2022 while the formal implementation of the PDCA manage-ment method was conducted in the PDCA management group from August to December in 2022.For the PDCA management group,PDCA management method was learned and pre-implementation conducted in July 2022.The chi-square test was used to analyze the differences in the rational medication rate,prescribing standardization and adverse reaction monitoring reports of psychotropic drugs between the conventional management group and the PDCA management group.The t-test was used to determine the differences in the pharmacy management quality score and prescription satisfaction score to assess the effectiveness of the application of the PDCA management method.Results After the implementation of PDCA management method,the rate of rational medication use increased from 93.50%(331/354)in the conventional management group to 97.54%(278/285)in the PDCA management group(P<0.05).The standardization of psychotropic drug prescribing improved,and the rate of prescribing errors decreased from 6.50%(23/354)in the conventional management group to 2.46%(7/285)in the PDCA management group(P<0.05).Pharmacy management quality score and prescription satisfaction score of the PDCA management group were(96.46±3.21),(96.33±2.42),respectively,which were higher than those of the conventional management group((82.57±5.92),(81.76±4.75),respectively)(both P<0.05).Meanwhile,the number of re-ported adverse reactions to psychotropic medications due to improper prescription and other reasons decreased from 5.65%(20/354)in the conventional management group to 2.11%(6/285)in the PDCA management group(P<0.05).Conclusion Pharmacists applying the PDCA management method to psychotropic drug prescriptions can improve the quality of prescription management and prescrip-tion satisfaction,reduce the management error rate and promote standardized prescription management.