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南刘寄奴的化学成分研究

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从南刘寄奴中分离并鉴定了14个化合物,分别为zhepiresinol (1), (-)-lariciresinol(2), ficusal(3), medioresinol (4),(+)-syringaresinol (5), 1β,2β-epoxy-3β,4α, 10α-trihydroxyguaian-6a,12-olide (6), 5β,10α-dihydroxy-1αH-dehydroleucodin (7),3α-chloro-8α-acetoxy-4β,10α-dihydroxy-1β,2β-epoxy-5α, 7αH-guai-11(13)-en-12,6α-olide(8), 13-O-desacetyl eudesma-afraglaucolide(9),1,10-seco-4]ξ-hydroxy-muurol-5-ene-1,10-diketone (10), 1α-hydroxyafraglaucolide (11), aurantiamide (12), indole-3-aldehyde (13),loliolide(14).所有化合物均为首次从该植物中分离得到,其中化合物1-4,8,10,13为首次从蒿属植物中分离得到.
Chemical ingredients isolated from the aerial parts of Artemisia anomala
Fourteen known compounds were isolated from the aerial parts of Artemisia anomala and identified as follows:zhepiresinol (1), (-)-lariciresinol (2), ficusal (3), medioresinol (4), (+)-syringaresinol (5), 1β,2β-epoxy-3β,4α, 10α-trihydroxyguaian-6α, 12-olide (6), 5β,10α-dihydroxy-1αH-dehydroleucodin (7), 3α-chloro-8α-acetoxy-4β,10α-dihydroxy-1β,2β-epoxy-5α,7αH-guai-11(13)-en-12,6α-olide (8), 13-O-desacetyleudesma-afraglaucolide (9), 1,10-seco-4ξ-hydroxy-muurol-5-ene-1,10-diketone (10),1α-hydroxyafraglaucolide(11), aurantiamide (12), indole-3-aldehyde (13), loliolide (14). All these compounds were isolated from this plant for the first time and compounds 1-4, 8, 10, 13 were obtained from genus Artemisia for the first time.

Artemisia anomalaCompositaeChemical constituentsLignansSesquiterpenoids

昝珂、陈筱清、付强、周思祥、肖美添、温晶、屠鹏飞

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中国药科大学,中药学院,江苏,南京,210009

北京大学医学部,天然药物及仿生药物国家重点实验室,北京,100191

华侨大学,化工与制药工程系,福建,泉州,361021

南刘寄奴 奇蒿 菊科 化学成分 木脂素 倍半萜

国家自然科学基金

30973629

2010

中国药学(英文版)
中国药学会

中国药学(英文版)

CSTPCD
影响因子:0.534
ISSN:1003-1057
年,卷(期):2010.19(2)
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