Exploring the impact of anti-diabetic medications on sarcopenia:a comprehensive review
Sarcopenia is a condition characterized by a reduction in muscle mass and/or diminished muscle function,significantly amplifying the risk of falls,fractures,and even mortality among the elderly.Although diabetes can be further complicated by sarcopenia,the precise cause and mechanism remain unclear.Moreover,the impact of anti-diabetic medications,commonly used by individuals with type 2 diabetes,extends beyond glycemic control.These drugs can influence skeletal muscle through diverse mechanisms,affecting the delicate balance between protein synthesis and breakdown,thereby contributing to the development of sarcopenia.This article delves into the potential mechanisms of anti-diabetic drugs on sarcopenia,offering insights from relevant clinical studies and data.
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