首页|氢气的药理学作用及其给药途径的研究进展

氢气的药理学作用及其给药途径的研究进展

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氢气是自然界中含量最丰富的元素,是无色、无味、无臭的气体,具有很强的还原性.目前的研究证实,氢气具有抗氧化、抗疲劳、抗辐射、抗炎和降糖降脂的作用,可以治疗各种缺血再灌注损伤、器官移植损伤、神经变性疾病、动脉粥样硬化和代谢综合征等多种疾病.氢气在水中的溶解度极低,一个大气压下氢气的饱和浓度为只有0.8 ppm,因此想要达到理想的氢气治疗浓度,就必须提高氢气的含量和提供合适的给药途径.氢气的给药方式有吸入法给氢、饮用富氢水、饱和氢生理盐水注射、增加体内氢气产生和口服固体释氢药物等.本文总结了氢气的药理学作用及其给药途径,为氢气在治疗应用上提供思路.
Advancements in pharmacological effects and administration routes of hydrogen gas:A comprehensive research overview
Hydrogen,the simplest element in the universe.Hydrogen gas is colorless,odorless,and tasteless.As a reducing agent composed of two atoms.It exhibits strong reducing power and possesses numerous pharmacological effects,including anti-oxidation,antifatigue,anti-radiation,anti-inflammation,hypoglycemic,and hypolipidemic effects.Various methods exist for supplying hydrogen,but inhaling the gas is dangerous,drinking hydrogen-rich water is ineffective,and injecting hydrogen-rich saline is inconvenient.The most viable approach for clinical use is oral medicine,which produces hydrogen in vivo.Hydrogen gas holds promising potential as a clinical medicine in the future.

Hydrogen gasPharmacological effectsAdministration routeResearch progress

张慧、张红梅、彭军、凌云

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解放军总医院医疗保障中心药剂科,北京 100048

河北燕达医院药学部,河北廊坊 065201

氢气 药理作用 给药途径 研究进展

2024

中国药学(英文版)
中国药学会

中国药学(英文版)

CSTPCD
影响因子:0.534
ISSN:1003-1057
年,卷(期):2024.33(6)
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